Masayuki Amagai Selected Research

Immunoglobulin G (IgG)

1/2022	IgM to IgG Class Switching Is a Necessary Step for Pemphigus Phenotype Induction in Desmoglein 3-Specific B Cell Receptor Knock-in Mouse.
1/2022	Intravenous Ig Regulates Anti-Desmoglein 3 IgG Production in B220- Antibody-Producing Cells in Mice with Pemphigus Vulgaris.
10/2020	Pemphigus Vulgaris and Foliaceus IgG Autoantibodies Directly Block Heterophilic Transinteraction between Desmoglein and Desmocollin.
1/2020	Autoimmune bullous skin diseases, pemphigus and pemphigoid.
1/2020	Is Local Production of Autoantibodies in Skin Lesions Relevant in Pemphigus?
1/2020	HaloTag-based conjugation of proteins to barcoding-oligonucleotides.
12/2019	Japanese guidelines for the management of pemphigoid (including epidermolysis bullosa acquisita).
2/2019	Rituximab therapy for refractory autoimmune bullous diseases: A multicenter, open-label, single-arm, phase 1/2 study on 10 Japanese patients.
1/2019	Autoimmunity and immunological tolerance in autoimmune bullous diseases.
1/2019	Abl family tyrosine kinases govern IgG extravasation in the skin in a murine pemphigus model.

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Masayuki Amagai Research Topics

Disease

90	Pemphigus (Pemphigus Vulgaris) 01/2022 - 01/2002
37	Blister (Bulla) 01/2022 - 05/2002
16	Atopic Dermatitis (Atopic Eczema) 12/2021 - 12/2007
15	Skin Diseases (Skin Disease) 09/2021 - 02/2003
13	Neoplasms (Cancer) 08/2021 - 09/2008
11	Autoimmune Diseases (Autoimmune Disease) 11/2020 - 09/2002
10	Dermatitis 11/2022 - 05/2010
10	Acantholysis 05/2017 - 01/2002
9	Bullous Pemphigoid (Pemphigoid) 12/2021 - 12/2002
9	Inflammation (Inflammations) 06/2021 - 05/2009
9	Impetigo (Impetigo Contagiosa) 03/2012 - 05/2002
9	Staphylococcal Scalded Skin Syndrome (Ritter's Disease) 03/2012 - 05/2002
7	Melanoma (Melanoma, Malignant) 12/2021 - 01/2015
5	Disease Progression 01/2022 - 05/2012
4	Hypersensitivity (Allergy) 08/2022 - 11/2013
4	Epidermolysis Bullosa Acquisita (Acquired Epidermolysis Bullosa) 12/2021 - 06/2011
4	Infections 01/2021 - 02/2003
4	Squamous Cell Carcinoma (Epidermoid Carcinoma) 10/2020 - 11/2006
4	Eczema 04/2015 - 05/2009
4	Asthma (Bronchial Asthma) 05/2014 - 08/2008
3	Fever (Fevers) 08/2022 - 06/2018
3	Palmoplantar Keratoderma (Keratosis Palmaris et Plantaris) 07/2017 - 03/2012
3	Contact Dermatitis (Eczema, Contact) 11/2015 - 05/2010
3	Ichthyosis Vulgaris (Dominant Ichthyosis Vulgaris) 01/2011 - 08/2008
2	Ichthyosis (Xeroderma) 11/2022 - 02/2013
2	Eosinophilia 08/2022 - 05/2014
2	Graft vs Host Disease (Graft-Versus-Host Disease) 08/2022 - 03/2019
2	Annular Erythema 10/2021 - 05/2004
2	Linear IgA Bullous Dermatosis 09/2021 - 01/2018
2	Rare Diseases (Rare Disease) 09/2021 - 09/2010
2	Stevens-Johnson Syndrome (Lyell's Syndrome) 07/2021 - 01/2019
2	Anaphylaxis (Anaphylactic Shock) 12/2020 - 10/2012
2	Neoplasm Metastasis (Metastasis) 01/2019 - 01/2015
2	Junctional Epidermolysis Bullosa (Epidermolysis Bullosa Letalis) 01/2018 - 04/2015
2	Epidermolysis Bullosa 01/2018 - 10/2007
2	Dysbiosis 01/2017 - 04/2015
2	Alopecia (Baldness) 01/2017 - 11/2013
2	Lymphoma (Lymphomas) 11/2015 - 06/2013
2	Alopecia Areata 11/2014 - 05/2010
2	Psoriasis (Pustulosis Palmaris et Plantaris) 09/2013 - 09/2003

Drug/Important Bio-Agent (IBA)

65	AutoantibodiesIBA 01/2022 - 01/2002
60	Immunoglobulin G (IgG)IBA 01/2022 - 01/2002
44	Desmoglein 3IBA 01/2022 - 01/2002
37	DesmogleinsIBA 01/2022 - 09/2002
27	AntibodiesIBA 12/2021 - 01/2002
21	AntigensIBA 12/2021 - 09/2002
20	Desmoglein 1IBA 01/2019 - 01/2002
18	Proteins (Proteins, Gene)FDA Link 01/2020 - 07/2002
15	AutoantigensIBA 12/2021 - 09/2002
15	EpitopesIBA 07/2015 - 02/2003
11	Pharmaceutical PreparationsIBA 08/2022 - 03/2009
11	EnzymesIBA 01/2022 - 01/2002
11	Filaggrin ProteinsIBA 11/2021 - 08/2008
11	Cadherins (E-Cadherin)IBA 01/2012 - 05/2002
10	Monoclonal AntibodiesIBA 10/2020 - 02/2003
8	ImmunosorbentsIBA 11/2013 - 01/2002
8	ExfoliatinsIBA 03/2012 - 05/2002
6	Immunoglobulin E (IgE)IBA 12/2021 - 05/2009
6	Immunoglobulin A (IgA)IBA 09/2021 - 01/2002
5	Nonsense Codon (Nonsense Mutation)IBA 08/2021 - 08/2008
5	Protein Isoforms (Isoforms)IBA 05/2017 - 08/2004
4	Desmosomal CadherinsIBA 01/2018 - 10/2002
4	Collagen Type VIIIBA 01/2018 - 10/2007
4	Cell Adhesion MoleculesIBA 01/2018 - 02/2003
4	SteroidsIBA 02/2017 - 02/2009
4	HaptensIBA 11/2015 - 05/2010
3	Intravenous Immunoglobulins (IVIG)FDA Link 01/2022 - 04/2009
3	Immunoglobulin M (IgM)IBA 01/2022 - 10/2004
3	Rituximab (Mabthera)FDA Link 12/2021 - 07/2017
3	Adrenal Cortex Hormones (Corticosteroids)IBA 09/2021 - 10/2011
3	Immune Checkpoint InhibitorsIBA 08/2021 - 01/2019
3	NivolumabIBA 10/2020 - 11/2016
3	Peptides (Polypeptides)IBA 01/2017 - 02/2004
3	Keratins (Keratin)IBA 09/2015 - 05/2004
3	Prednisolone (Predate)FDA LinkGeneric 03/2013 - 10/2005
3	Glycoproteins (Glycoprotein)IBA 03/2012 - 12/2003
2	Imatinib Mesylate (Gleevec)FDA Link 12/2021 - 01/2019
2	Tacrolimus (Prograf)FDA LinkGeneric 12/2021 - 09/2003
2	Hydroxychloroquine (Plaquenil)FDA LinkGeneric 10/2021 - 03/2013
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 08/2021 - 11/2008
2	ChemokinesIBA 08/2021 - 01/2011
2	NucleotidesIBA 02/2021 - 04/2015
2	Interleukin-17 (Interleukin 17)IBA 01/2021 - 09/2013
2	DesmocollinsIBA 10/2020 - 12/2010
2	InterleukinsIBA 06/2018 - 05/2014
2	Vancomycin FDA LinkGeneric 01/2018 - 01/2017
2	Methotrexate (Mexate)FDA LinkGeneric 09/2017 - 02/2014
2	Anti-Bacterial Agents (Antibiotics)IBA 01/2017 - 04/2015
2	Dapsone FDA Link 01/2017 - 02/2009
2	Carboplatin (JM8)FDA LinkGeneric 01/2017 - 09/2015
2	CytokinesIBA 11/2015 - 05/2014
2	Recombinant ProteinsIBA 07/2015 - 01/2006
2	ErbB Receptors (EGF Receptor)IBA 04/2015 - 03/2013
2	Messenger RNA (mRNA)IBA 01/2015 - 01/2015
2	ElementsIBA 06/2014 - 03/2010
2	Immunoglobulins (Immunoglobulin)IBA 05/2014 - 03/2010

Therapy/Procedure

20	Therapeutics 12/2021 - 04/2003
4	Drug Therapy (Chemotherapy) 03/2020 - 09/2013
2	Stem Cell Transplantation 03/2019 - 10/2005
2	Transplantation 01/2018 - 10/2012